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Research Animal Models > Disease & Translational Models
 
 
Common Name Nomenclature Species
Cardiovascular Research Models
11BHSD2* C57BL/6NCrl-Tg(aMhc-Hsd11b2) Mouse
APOA1* B6;CBA-Tg(APOA1)427Bres/Crl Mouse
LOX-1* C57/BL6J-Tg(OLR1) Mouse
Spontaneously Hypertensive Heart Failure (SHHF)$ SHHF/MccGmiCrl-Leprcp/Crl Rat
Click here for surgically altered cardiovascular models.
     
CNS Research Models    
NSE-p25* FVB/N-Tg(Eno2-CDKSr1)1Jdm Mouse
P-glycoprotein Deficient (PGP) Crl:CF1-Abcb1amds Mouse
Click here for surgically altered CNS models.
     
Diabetes Research Models    
GLUT 4* C57BL/KsJ-db/db-Tg(SLC2a4)1Jdm Mouse
Goto-Kakizaki (GK)$ GK/TohiCskCrljCrl Rat
GSK3B* FVB/N-Tg(Mic2-tTA-GSK3) Mouse
Spontaneously Hypertensive Heart Failure (SHHF)$ SHHF/MccGmiCrl-Leprcp/Crl Rat
Rip-HAT* FVB/N-Tg(Ins2-IAPP)RHF Soel Mouse
RIP-HAT* CD:SD-Tg(ins2-IAPP)Soel Rat
ZSF1$ ZSF1-LeprfaLeprcp/Crl Rat
Zucker Diabetic Fatty (ZDF)$€ ZDF-Leprfa/Crl Rat
     
Immunology and Inflammation Research Models
Ly5$€ B6.SJL-PtprcaPepcb/BoyCrl Mouse
MMP9* FVB/N-Tg(Eno2-MMP9) Mouse
OT I C57BL/6-Tg(TcraTcrb)1100Mjb/Crl Mouse
OT II C57BL/6-Tg(TcraTcrb)425Cbn/Crl Mouse
     
Metabolism and Regulation Research Models
Bcrp$ Crl:WI(UL)-Abcg2tm1/Hubr Rat
Dahl/Salt Sensitive (DAHL/SS)$ SS/JrHsdMcwiCrl Rat
Goto-Kakizaki (GK)$ GK/TohiCskCrljCrl Rat
HSD11B1* FVB/N-Tg(AP2-HSD11b1) Mouse
LCAT* C57BL/6J-Tg(Alb-LCAT)1Jdm Mouse
Obese Prone CD (OP-CD)$ Crl:OP(CD) Rat
Obese Resistant CD (OR-CD)$ Crl:OR(CD) Rat
PCSK9* C57BL/6J-Tg(ALB-PCSK9) Mouse
Spontaneously Hypertensive Heart Failure (SHHF)$ SHHF/MccGmiCrl-Leprcp/Crl Rat
Spontaneously Hypertensive (SHR)$€ SHR/NCrl Rat
Spontaneously Hypertensive Obese (SHROB)$ SHROB/KolGmiCrl-Leprcp/Crl$ Rat
Spontaneously Hypertensive Stroke Prone (SHRSP)$ SHRSP/A3NCrl Rat
THE POUND MOUSE$€ C57BL/6NCrl-Leprdb-lb/Crl Mouse
ZSF1$ ZSF1-LeprfaLeprcp/Crl Rat
Zucker$€ Crl:ZUC-Leprfa Rat
Zucker Diabetic Fatty (ZDF)$€ ZDF-Leprfa/Crl Rat
     
Oncology Research Models    
129 D931A* 129P2.B6J-Pik3cbtm3Bvan/Crl Mouse
129 flox* 129P2.B6J-Pik3cbtm1.1Bvan/Crl Mouse
AKR* AKR/NCrl Mouse
B6 D910A* B6J.129P2-Pik3cdtm2Bvan/Crl Mouse
B6 D931A* B6J.129P2-Pik3cbtm3Bvan/Crl Mouse
B6 D933A* B6J.129P2-Pik3catm2Bvan/Crl Mouse
B6 flox* B6J.129P2-Pik3cbtm1.1Bvan/Crl Mouse
B6 lacZ* B6J.129P2-Pik3catm3Bvan/Crl Mouse
B6 lacZ D931A* B6J.129P2-Pik3cbtm2Bvan/Crl Mouse
B6 S1031A* B6J.129P2-Pik3cdtm3Bvan/Crl Mouse
BDIX* BDIX/CrCrl Rat
Buffalo$ BUF/CrCrl Rat
C D910A* C.129P2(B6)-Pik3cdtm2Bvan/Crl Mouse
C D931A* C.129P2(B6)-Pik3cbtm3Bvan/Crl Mouse
Immortomouse®$ CBA;B10-Tg(H2Kb-tsA58)6Kio/Crl Mouse
lacZ* B6J.129P2-Pik3cdtm1Bvan/Crl Mouse
Noble* NBL/CrCrl Rat
p110alpha flox* B6J.129P2-Pik3catm1Bvan/Crl Mouse
p110beta flox* B6J.129P2-Pik3cbtm1Bvan/Crl Mouse
p53$ Crl:WI(UL)-Tp53tm1/Hubr Rat
Wistar Furth* WF/CrCrl Rat
     
Legends    
$€ Bred in U.S. and E.U.    
$ Bred in U.S.    
€ Bred in E.U.    
*Cryopreserved    
 
 
 
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